SCHEMBL5607428

SCHEMBL5607428

CNC(=O)CCC(=O)NCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.70
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
L3MBTL1 Q9Y468 3/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2C19 P33261 1/20 0.68
ALDH1A1 P00352 4/20 0.67
EPHX2 P34913 1/20 0.63
HTT P42858 1/20 0.62
TSHR P16473 3/20 0.58
HPGD P15428 2/20 0.58
RECQL P46063 1/20 0.58
POLB P06746 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
TRPV1 Q8NER1 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796377 0.93 GAA (0.83) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL13620016 0.87 GAA (0.61) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL6307396 0.85 GAA (0.70) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL93948 0.85 GAA (0.75) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL14754215 0.84 GAA (0.68) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL770934 0.83 CYP3A4 (0.87) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL2942358 0.82 MEN1 (0.96) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL23260509 0.82 GAA (0.57) GAAALDH1A1HTTTSHRHPGD
SCHEMBL4900724 0.81 GAA (0.70) GAAMEN1KMT2AL3MBTL1CYP3A4
SCHEMBL7353744 0.81 GAA (0.75) GAAMEN1KMT2AL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP GAA 473/4885MEN1 808/4885KMT2A 3688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.