Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476509 | 0.89 | GAA (0.83) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL30992146 | 0.89 | MEN1 (0.80) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL5607428 | 0.85 | GAA (0.70) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL93948 | 0.85 | GAA (0.75) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL7126303 | 0.85 | GAA (0.63) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| Acetic Acid SCHEMBL29696065 | 0.84 | CYP3A4 (0.81) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL770934 | 0.83 | CYP3A4 (0.87) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL2942358 | 0.82 | MEN1 (0.96) | GAAMEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL8269430 | 0.82 | TPSAB1 (0.83) | GAAL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL27891875 | 0.82 | ALDH1A1 (0.53) | GAAMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-12-24 | — | — | US | disclosed |
| WO-2013029479-A1 | MYCOPHENOLIC ACID DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 中国科学院上海药物研究所 (CN) | 2013-03-07 | — | — | WO | disclosed |
| US-6849767-B2 | Method of hydroborating alcohols and reducing functional groups using a recyclable fluorous borane-sulfide | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040116747-A1 | Method of hydroborating alcohols and reducing functional groups using a recyclable fluorous borane-sulfide | UNIVERSITY OF ILLINOIS AT CHICAGO | 2004-06-17 | — | — | US | disclosed |
| WO-2004011472-A2 | METHOD OF HYDROBORATING ALCOHOLS AND REDUCING FUNCTIONAL GROUPS USING A RECYCLABLE FLUOROUS BORANE-SULFIDE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399634-A1 | DNA-TEMPLATED MACROCYCLE LIBRARY | IDE, IAPP, POLRMT | GAA 115/4885MEN1 3644/4885KMT2A 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.