Benzimidazole

Benzimidazole

SCHEMBL5607614

Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.c1ccc2[nH]cnc2c1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
PARP1 P09874 2/20 0.37
PDPK1 O15530 1/20 0.37
CA12 O43570 1/20 0.37
ALOX15 P16050 1/20 0.37
CA9 Q16790 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
PRKCI P41743 1/20 0.37
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
RAB9A P51151 2/20 0.36
HTT P42858 2/20 0.36
QPCT Q16769 2/20 0.36
QPCTL Q9NXS2 1/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 2/20 0.36
RAD52 P43351 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL3446604 1.00 POLB (0.38) POLBSMN1; SMN2PARP1PDPK1CA12
Benzimidazole SCHEMBL8956495 0.81 SMN1; SMN2 (0.44) SMN1; SMN2PARP1PDPK1CA12ALOX15
Benzimidazole SCHEMBL4305084 0.81 SMN1; SMN2 (0.44) SMN1; SMN2PARP1PDPK1CA12ALOX15
Benzimidazole SCHEMBL29358377 0.81
Benzimidazole SCHEMBL461969 0.81 SMN1; SMN2 (0.50) SMN1; SMN2PARP1PDPK1CA12ALOX15
Benzimidazole SCHEMBL29408372 0.81
Benzimidazole SCHEMBL6009 0.81
Benzimidazole SCHEMBL10931770 0.81 SMN1; SMN2 (0.50) SMN1; SMN2PARP1PDPK1CA12ALOX15
Benzimidazole SCHEMBL23673327 0.79 SMN1; SMN2 (0.48) SMN1; SMN2PARP1PDPK1CA12ALOX15
Benzimidazole SCHEMBL20531480 0.79 SMN1; SMN2 (0.48) SMN1; SMN2PARP1PDPK1CA12ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228109-B1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS DOW GLOBAL TECHNOLOGIES INC (US) 2006-02-01 EP claimed
US-6716786-B1 LEWIS ACIDS AND BASES THE DOW CHEMICAL COMPANY 2004-04-06 US claimed
EP-1228109-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2002-08-07 EP claimed
WO-2001023442-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2001-04-05 WO claimed
EP-1753796-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2007-02-21 EP disclosed
EP-1228109-B1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS DOW GLOBAL TECHNOLOGIES INC (US) 2006-02-01 EP disclosed
WO-2005113622-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-12-01 WO disclosed
US-6716786-B1 LEWIS ACIDS AND BASES THE DOW CHEMICAL COMPANY 2004-04-06 US disclosed
EP-1228109-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2002-08-07 EP disclosed
WO-2001023442-A1 SUPPORTED CATALYST COMPRISING EXPANDED ANIONS THE DOW CHEMICAL COMPANY (US) 2001-04-05 WO disclosed