Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 9/20 | 0.52 |
| ▸ | RXRA | P19793 | 9/20 | 0.52 |
| ▸ | RXRG | P48443 | 6/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075914 | 0.96 | RXRA (0.52) | RXRBRXRARXRGMRGPRX4ADRA2A | |
| SCHEMBL2416358 | 0.86 | RXRB (0.50) | RXRBRXRARXRGMRGPRX4ADRA2A | |
| SCHEMBL9719997 | 0.81 | RXRA (0.55) | RXRBRXRARXRGMRGPRX4ADRA2A | |
| SCHEMBL2204938 | 0.81 | RXRA (0.49) | RXRBRXRARXRGMRGPRX4BCL2L1 | |
| SCHEMBL9492175 | 0.80 | RXRA (0.51) | RXRBRXRARXRGMRGPRX4BCL2L1 | |
| SCHEMBL19330870 | 0.79 | RXRA (0.50) | RXRBRXRARXRGMRGPRX4ADRA2A | |
| SCHEMBL11015470 | 0.79 | RXRB (0.50) | RXRBRXRARXRGMRGPRX4SSTR4 | |
| SCHEMBL5456652 | 0.79 | RXRA (0.50) | RXRBRXRARXRGMRGPRX4ADRA2A | |
| SCHEMBL30994276 | 0.79 | RXRA (0.50) | RXRBRXRARXRGMRGPRX4ADRA2A | |
| SCHEMBL6573511 | 0.79 | RXRB (0.50) | RXRBRXRARXRGMRGPRX4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022233-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009473-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| EP-1833859-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006065843-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |