Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607860 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AHTTALDH1A1SLC7A5 | |
| SCHEMBL5607751 | 0.89 | MMP13 (0.63) | SMN1; SMN2KMT2AHTTALDH1A1SLC7A5 | |
| SCHEMBL5607748 | 0.89 | MMP13 (0.63) | SMN1; SMN2KMT2AHTTALDH1A1SLC7A5 | |
| SCHEMBL5607255 | 0.83 | HTR2C (0.61) | SLC7A5EPHX2PPARGPPARACHRM3 | |
| SCHEMBL5607247 | 0.83 | HTR2C (0.61) | SLC7A5EPHX2PPARGPPARACHRM3 | |
| SCHEMBL5606497 | 0.82 | CA1 (0.62) | KMT2AALDH1A1SLC7A5EPHX2PPARG | |
| SCHEMBL5606488 | 0.82 | CA1 (0.62) | KMT2AALDH1A1SLC7A5EPHX2PPARG | |
| SCHEMBL8233853 | 0.81 | MMP13 (0.46) | SMN1; SMN2KMT2AHTTALDH1A1SLC7A5 | |
| SCHEMBL5607171 | 0.81 | SLC7A5 (0.55) | SMN1; SMN2KMT2AALDH1A1SLC7A5EPHX2 | |
| SCHEMBL5607177 | 0.81 | SLC7A5 (0.55) | SMN1; SMN2KMT2AALDH1A1SLC7A5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238669-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY | 2007-10-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238669-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS | GLP1R, GIPR, IAPP | SMN1; SMN2 1582/4885KMT2A 3688/4885HTT 1492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.