Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29160858 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL8928288 | 0.84 | TRPV1 (0.39) | ALDH1A1ALOX15HSD17B10LMNAHTT | |
| SCHEMBL28710912 | 0.83 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL25382540 | 0.83 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL466221 | 0.83 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL7081344 | 0.81 | TRPV1 (0.39) | ALDH1A1ALOX15HSD17B10LMNAHTT | |
| SCHEMBL29431941 | 0.80 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL597699 | 0.78 | ALDH1A1 (0.59) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL8845948 | 0.78 | ALDH1A1 (0.59) | ALDH1A1ALOX15HSD17B10HPGDTDP1 | |
| SCHEMBL1134579 | 0.78 | ALDH1A1 (0.59) | ALDH1A1ALOX15HSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831308-A1 | THERMOPLASTIC POLYCARBONATE COMPOSITIONS, ARTICLES MADE THEREFROM AND METHOD OF MANUFACTURE | General Electric Company (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006071488-A1 | THERMOPLASTIC POLYCARBONATE COMPOSITIONS, ARTICLES MADE THEREFROM AND METHOD OF MANUFACTURE | GENERAL ELECTRIC COMPANY (US) | 2006-07-06 | — | — | WO | disclosed |
| US-20060142486-A1 | Thermoplastic polycarbonate compositions, articles made therefrom and method of manufacture | CITIBANK, N.A., AS COLLATERAL AGENT | 2006-06-29 | — | — | US | disclosed |