SCHEMBL560812

SCHEMBL560812

BrCc1ccccc1I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506108 1.00
SCHEMBL808852 0.97 TAAR1 (0.50)
SCHEMBL29049182 0.89 TAAR1 (0.43)
SCHEMBL7373618 0.79 TAAR1 (0.60)
SCHEMBL29382225 0.78 TSHR (0.50)
SCHEMBL28289 0.78 TSHR (0.50)
SCHEMBL19657170 0.77 GABRA1 (0.41)
SCHEMBL3871871 0.77 TAAR1 (0.37)
SCHEMBL31057408 0.77 TAAR1 (0.37)
SCHEMBL29581892 0.77 GABRA1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586440-B Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-04-09 CN claimed
CN-117586440-A Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-02-23 CN claimed
CN-108863894-A A kind of method of the direct synthesis of indole of nitrile 中国科学技术大学 2018-11-23 CN claimed
CN-107935842-A A kind of preparation method of 2 chlorine, 4 bromine, 6 methyl benzoic acid 珠海奥博凯生物医药技术有限公司 2018-04-20 CN claimed
US-12595272-B2 Methods to produce organotin compositions with convenient ligand providing reactants INPRIA CORPORATION (US) 2026-04-07 US disclosed
US-20260049094-A1 METHODS TO PRODUCE ORGANOTIN COMPOSITIONS WITH CONVENIENT LIGAND PROVIDING REACTANTS INPRIA CORP (US) 2026-02-19 US disclosed
US-20260042786-A1 METHODS TO PRODUCE ORGANOTIN COMPOSITIONS WITH CONVENIENT LIGAND PROVIDING REACTANTS INPRIA CORP (US) 2026-02-12 US disclosed
EP-4587438-A1 BICYCLIC COMPOUNDS AS CDK INHIBITORS BeiGene Switzerland GmbH (CH) 2025-07-23 EP disclosed
CN-119977947-A PRMT5 inhibitor, pharmaceutical composition thereof and application of PRMT5 inhibitor in medicines 广东东阳光药业股份有限公司 2025-05-13 CN disclosed
CN-119912362-A Isosteviol derivative and application thereof in preparation of anticancer drugs 上海海洋大学 2025-05-02 CN disclosed
CN-119894890-A Bicyclic compounds as CDK inhibitors 百济神州(苏州)生物科技有限公司 2025-04-25 CN disclosed
US-20250066357-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2025-02-27 US disclosed
US-4857553-A SIDE EFFECT REDUCTION A. H. ROBINS COMPANY, INCORPORATED (US) 1989-08-15 US disclosed
EP-0302757-A2 Anti-emetic serotonin depleting agents A.H. ROBINS COMPANY, INCORPORATED (US) 1989-02-08 EP disclosed
EP-0011858-B1 RADIOIODINE CONTAINING AMINES, THEIR PREPARATION AND THEIR USE AS BRAIN IMAGING AGENTS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-05-18 EP disclosed
US-4360511-A Amines useful as brain imaging agents MEDI-PHYSICS, INC. (US) 1982-11-23 US disclosed
US-4227004-A Synthesis of substituted 1-aralkyl-1H-v-triazoles ICI AMERICAS INC. (US) 1980-10-07 US disclosed
EP-0011858-A1 Radioiodine containing amines, their preparation and their use as brain imaging agents F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-06-11 EP disclosed
US-3954973-A ALKYL HALIDES AMERICAN CYANAMID COMPANY (US) 1976-05-04 US disclosed
US-3953597-A POULTRY FEEDS INTERNATIONAL MINERALS & CHEMICAL CORPORATION (US) 1976-04-27 US disclosed