Dimethylamine

Dimethylamine

SCHEMBL5608192

CNC.c1ccc(-n2ccc3ccccc32)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.61
PRKD3 O94806 1/20 0.46
PRKCG P05129 1/20 0.46
PRKCB P05771 1/20 0.46
PRKCA P17252 1/20 0.46
PRKACA P17612 1/20 0.46
PRKACG P22612 1/20 0.46
PRKACB P22694 1/20 0.46
PRKCH P24723 1/20 0.46
PRKCI P41743 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCZ Q05513 1/20 0.46
PRKCD Q05655 1/20 0.46
PRKD1 Q15139 1/20 0.46
PLA2G4A P47712 1/20 0.43
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
BRD4 O60885 1/20 0.42
BRPF1 P55201 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170890 0.92 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL29475118 0.92 BIRC5 (0.70) BIRC5PRKD3PRKCGPRKCBPRKCA
Phosphine SCHEMBL28297804 0.90 BIRC5 (0.68) BIRC5PRKD3PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL3803742 0.90 BIRC5 (0.68) BIRC5PRKD3PRKCGPRKCBPRKCA
Hydrochloric Acid SCHEMBL15066336 0.88 BIRC5 (0.66) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL13105711 0.83 BIRC5 (0.61) BIRC5PRKD3PRKCGPRKCBPRKCA
Aniline SCHEMBL22656869 0.82 BIRC5 (0.59) BIRC5PRKD3PRKCGPRKCBPRKCA
Ether SCHEMBL6529480 0.82 BIRC5 (0.54) BIRC5PRKD3PRKCGPRKCBPRKCA
Toluene SCHEMBL23051706 0.81 BIRC5 (0.62) BIRC5PRKD3PRKCGPRKCBPRKCA
SCHEMBL5792785 0.80 BIRC5 (0.67) BIRC5PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1354887-B1 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INST TECHNOLOGY (US) 2007-04-25 EP disclosed
EP-1097158-B1 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INST TECHNOLOGY (US) 2006-01-25 EP disclosed