Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608040 | 0.96 | TSHR (0.41) | TSHRHSD17B10PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL4036133 | 0.96 | TSHR (0.44) | TSHRHSD17B10PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL5608250 | 0.89 | NPSR1 (0.35) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL4037047 | 0.87 | PKM (0.50) | TSHRHSD17B10PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL5608197 | 0.87 | NPSR1 (0.34) | MEN1KMT2ALMNANPSR1 | |
| SCHEMBL20345497 | 0.87 | TSHR (0.48) | TSHRHSD17B10PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL27153985 | 0.87 | NPSR1 (0.37) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL4036128 | 0.86 | TSHR (0.35) | TSHRHSD17B10PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL4102881 | 0.86 | SMN1; SMN2 (0.34) | TSHRHSD17B10PKMSMN1; SMN2RAB9A | |
| SCHEMBL5608339 | 0.85 | NPSR1 (0.35) | TSHRHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39744-E1 | Adamantane derivatives and process for producing them | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-24 | — | — | US | disclosed |
| US-6392104-B1 | CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| EP-0927711-A1 | ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM | Daicel Chemical Industries, Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |