SCHEMBL5608381

SCHEMBL5608381

CCSN(SCC)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10822937 0.97 FFAR3 (0.33) FFAR3ALDH1A1TSHRMAPK1
SCHEMBL4631571 0.79 ALDH1A1 (0.35) FFAR3ALDH1A1TSHRMAPK1HPGD
SCHEMBL3257895 0.78 FFAR3 (0.32) FFAR3ALDH1A1TSHRMAPK1
SCHEMBL6907435 0.78 TDP1 (0.39) FFAR3ALDH1A1TSHRMAPK1HDAC3
SCHEMBL8622479 0.78
SCHEMBL7122582 0.77 ALDH1A1 (0.35) FFAR3ALDH1A1TSHRMAPK1HPGD
Hydrochloric Acid SCHEMBL10823079 0.76 TDP1 (0.37) FFAR3ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL4557462 0.74 TSHR (0.32) ALDH1A1TSHRMAPK1
SCHEMBL10822936 0.74 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1
SCHEMBL4184059 0.74 TSHR (0.36) ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070105139-A1 Fluorescent probe and fluorescence detecting method FUJIFILM CORPORATION (JP) 2007-05-10 US disclosed
EP-1021434-A2 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND USE Krenitsky Pharmaceuticals, Inc. (US) 2000-07-26 EP disclosed
WO-1998012190-A2 PHENOXATHIIN DERIVATIVES AS INHIBITORS OF MONOAMINE OXIDASE KRENITSKY PHARMACEUTICAL, INC. (US) 1998-03-26 WO disclosed