SCHEMBL5608552

SCHEMBL5608552

COC(=O)OC12CC3CC(OC(=O)OC)(C1)CC(OC(=O)OC)(C3)C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33
GLA P06280 1/20 0.32
NAAA Q02083 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5608441 0.91 DPP4 (0.31)
SCHEMBL7630280 0.89 GRIN1 (0.37) NPSR1NAAATSHR
SCHEMBL5608031 0.88 NPSR1 (0.39) NPSR1GLANAAAALDH1A1TSHR
SCHEMBL5608698 0.88 ALDH1A1 (0.38) GLAALDH1A1
SCHEMBL5607961 0.87 DPP4 (0.34)
SCHEMBL5608390 0.83 MAPT (0.30)
SCHEMBL3125283 0.83 NPSR1 (0.47) NPSR1GLANAAAALDH1A1TSHR
SCHEMBL18469162 0.81 DPP4 (0.41) NPSR1GLANAAAALDH1A1TSHR
SCHEMBL1696580 0.81 DPP4 (0.41) NPSR1GLANAAAALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL28325233 0.81 NPSR1 (0.45) NPSR1GLANAAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39744-E1 Adamantane derivatives and process for producing them DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-24 US disclosed
US-6392104-B1 CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-21 US disclosed
EP-0927711-A1 ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM Daicel Chemical Industries, Ltd. (JP) 1999-07-07 EP disclosed