Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.54 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.53 |
| ▸ | ITGAV | P06756 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850695 | 0.92 | ITGA4 (0.58) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL4423030 | 0.92 | ITGA4 (0.58) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL3858016 | 0.91 | ITGB1 (0.54) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL3849716 | 0.90 | CACNA1B (0.45) | ITGB1ITGA4ITGB7ITGA5LMNA | |
| SCHEMBL3852748 | 0.89 | ITGB1 (0.53) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL23519701 | 0.86 | ITGB1 (0.66) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL19678622 | 0.86 | ITGB1 (0.66) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL6429531 | 0.86 | ITGB1 (0.66) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL19661136 | 0.86 | ITGB1 (0.66) | ITGB1ITGA4ITGB7ITGA5ITGAV | |
| SCHEMBL19678647 | 0.86 | ITGB1 (0.66) | ITGB1ITGA4ITGB7ITGA5ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592386-A4 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARM INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1592386-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | Elan Pharmaceuticals, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004066931-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | disclosed |
| EP-1000051-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006390-A1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |