Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 9/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 5/20 | 0.37 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851934 | 0.86 | ITGA4 (0.41) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6452893 | 0.86 | ITGA4 (0.48) | ITGA4ITGB1ITGB7HCRTR1HCRTR2 | |
| SCHEMBL4412675 | 0.85 | KDM4E (0.40) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7390739 | 0.84 | ITGA4 (0.43) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL4413756 | 0.81 | ITGB1 (0.53) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL5608873 | 0.81 | ITGB1 (0.44) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL3859957 | 0.78 | ITGB1 (0.47) | ITGA4ITGB1ITGB7TACR1ITGA2 | |
| SCHEMBL3852324 | 0.77 | ITGB1 (0.47) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7408832 | 0.76 | ITGB1 (0.47) | ITGA4ITGB1ITGB7TACR1ITGA2 | |
| SCHEMBL3857293 | 0.76 | ITGB1 (0.45) | ITGA4ITGB1ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592386-A4 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARM INC (US) | 2007-06-13 | — | — | EP | claimed |
| EP-1592386-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | Elan Pharmaceuticals, Inc. (US) | 2005-11-09 | — | — | EP | claimed |
| WO-2004066931-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | claimed |