Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370209 | 0.96 | KCNN4 (0.54) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL864064 | 0.86 | SMN1; SMN2 (0.58) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL8392798 | 0.84 | SMN1; SMN2 (0.52) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL29017954 | 0.84 | SMN1; SMN2 (0.56) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL18635600 | 0.79 | L3MBTL1 (0.57) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL4379933 | 0.79 | CHRM2 (0.47) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL1649314 | 0.79 | CHRM2 (0.47) | KCNN4SMN1; SMN2L3MBTL1CHRM2MEN1 | |
| SCHEMBL31324682 | 0.77 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1CHRM2MEN1KMT2A | |
| SCHEMBL13053153 | 0.77 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1CHRM2MEN1KMT2A | |
| SCHEMBL4327683 | 0.77 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1CHRM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-B1 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |