SCHEMBL5609258

SCHEMBL5609258

C=C(C)CCl.CC(=O)CC(C)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.65
HSD17B10 Q99714 1/20 0.65
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
HTT P42858 1/20 0.36
ALDH1A1 P00352 6/20 0.35
TSHR P16473 3/20 0.35
KDM4E B2RXH2 2/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
TRPA1 O75762 1/20 0.33
HIF1A Q16665 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9201679 0.81
SCHEMBL8440977 0.80
SCHEMBL80580 0.80
SCHEMBL5339545 0.80
1,2-Dichloroethane SCHEMBL11594598 0.78 MGAM (0.45) TDP1HSD17B10MGAMGAASI
SCHEMBL607727 0.78
Dimethylamine SCHEMBL28688114 0.78
Hydrochloric Acid SCHEMBL25177388 0.77
Ammonia Solution, Strong SCHEMBL11226561 0.77
SCHEMBL11419191 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206430-B1 SYNTHESIS OF ALKENE-2-ONES BOULDER SCIENT CO (US) 2007-03-28 EP disclosed
US-6225506-B1 WHEN REACTING AN 2-ALKENE HALIDE AND A 2,4-ALKENEDIONE, THE USE OF AN ALKYLENE GLYCOL ENABLES SEPARATION OF THE HIGH-BOILING SOLVENT AND LOW BOILING PRODUCT BY DISTILLATION; ONE POT PROCESS BOULDER SCIENTIFIC COMPANY 2001-05-01 US disclosed