⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609258 | 0.80 | TDP1 (0.65) | — | |
| SCHEMBL15468632 | 0.74 | — | — | |
| SCHEMBL11181308 | 0.74 | — | — | |
| SCHEMBL3833068 | 0.74 | TDP1 (0.41) | — | |
| SCHEMBL183408 | 0.73 | — | — | |
| SCHEMBL12927368 | 0.72 | KDM4E (0.44) | — | |
| Chloroacetone SCHEMBL28597853 | 0.72 | — | — | |
| Chloroacetone SCHEMBL29249671 | 0.72 | — | — | |
| Chloroacetone SCHEMBL11195694 | 0.71 | ALDH1A1 (0.50) | — | |
| Chloroacetone SCHEMBL19827 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288650-B2 | Cyclic substituted fused pyrrolocarbazoles and isoindolones | CEPHALON, INC. (US) | 2007-10-30 | — | — | US | disclosed |
| US-7074793-B2 | Cyclic substituted fused pyrrolocarbazoles and isoindolones | CEPHALON, INC. (US) | 2006-07-11 | — | — | US | disclosed |
| US-20060128780-A1 | Cyclic substituted fused pyrrolocarbazoles and isoindolones | CEPHALON, INC. (US) | 2006-06-15 | — | — | US | disclosed |
| US-6841567-B1 | Cyclic substituted fused pyrrolocarbazoles and isoindolones | CEPHALON, INC. (US) | 2005-01-11 | — | — | US | disclosed |
| US-20040186157-A1 | Cyclic substituted fused pyrrolocarbazoles and isoindolones | CEPHALON, INC. (US) | 2004-09-23 | — | — | US | disclosed |
| CN-1350537-A | Cyclic substituted fused pyrrolocarbazoles and isoindolones | CEPHALON INC (US) | 2002-05-22 | — | — | CN | disclosed |
| EP-1165562-A1 | CYCLIC SUBSTITUTED FUSED PYRROLOCARBAZOLES AND ISOINDOLONES | Cephalon, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000047583-A9 | CYCLIC SUBSTITUTED FUSED PYRROLOCARBAZOLES AND ISOINDOLONES | CEPHALON INC (US) | 2001-09-20 | — | — | WO | disclosed |
| WO-2000047583-A1 | CYCLIC SUBSTITUTED FUSED PYRROLOCARBAZOLES AND ISOINDOLONES | CEPHALON, INC. (US) | 2000-08-17 | — | — | WO | disclosed |