SCHEMBL5609286

SCHEMBL5609286

CCC1=Cc2c(ccc(-c3ccccc3)c2-c2ccccc2CC)C1C[SiH2]CC1C(CC)=Cc2c1ccc(-c1ccccc1)c2-c1ccccc1CC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
PTPN5 P54829 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609572 0.88 PDCD1 (0.35) PDCD1CD274PTPN5
SCHEMBL3818126 0.83 PDCD1 (0.31) PDCD1CD274
SCHEMBL4001907 0.82 PDCD1 (0.30) PDCD1CD274
SCHEMBL5609229 0.81
SCHEMBL5609361 0.79
SCHEMBL7058317 0.78
SCHEMBL5608882 0.78 ELANE (0.34)
SCHEMBL5610171 0.78 PDCD1 (0.31) PDCD1CD274
SCHEMBL7110028 0.78 GABRA1 (0.33)
SCHEMBL7158422 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-B1 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEM PATENTS INC (US) 2007-07-25 EP disclosed