SCHEMBL5609392

SCHEMBL5609392

CCC1=Cc2c(ccc(CC)c2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)C1C[SiH2]CC1C(CC)=Cc2c1ccc(CC)c2-c1cc(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5609987 0.85 RXRA (0.30) RXRARXRB
SCHEMBL5609593 0.84
SCHEMBL5609260 0.83
SCHEMBL5610325 0.82 RXRA (0.31) RXRARXRB
SCHEMBL5609555 0.79
SCHEMBL5610298 0.78 IKBKB (0.33) RXRARXRB
SCHEMBL5721586 0.77
SCHEMBL5610434 0.77
SCHEMBL5615004 0.76 RXRA (0.30) RXRARXRB
SCHEMBL5610229 0.75 RXRA (0.31) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-B1 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEM PATENTS INC (US) 2007-07-25 EP disclosed