Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14696671 | 0.93 | MAPT (0.43) | EPHX2MAPTHPGDGRIN2DGRIN3B | |
| SCHEMBL25398209 | 0.87 | GRIN2D (0.45) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25398211 | 0.87 | GRIN2D (0.45) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6904455 | 0.85 | MAPT (0.44) | MAPTHPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5713357 | 0.85 | GRIN2D (0.47) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL657934 | 0.79 | GRIN2D (0.62) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5000664 | 0.79 | GRIN2D (0.45) | EPHX2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27620610 | 0.79 | GRIN2D (0.59) | EPHX2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8947159 | 0.79 | GRIN2D (0.59) | EPHX2MAPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4301888 | 0.79 | GRIN2D (0.59) | EPHX2MAPTGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789376-A1 | SYNTHESIS PROCESS FOR 2-(3-HYDROXY-1-ADAMANTYL)-2-OXOACETIC ACID | ALBEMARLE CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006034175-A1 | SYNTHESIS PROCESS FOR 2-(3-HYDROXY-1-ADAMANTYL)-2-OXOACETIC ACID | ALBEMARLE CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |