Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14696671 | 0.89 | MAPT (0.43) | MAPTHPGDPKMGRIN2DGRIN3B | |
| SCHEMBL5609729 | 0.85 | EPHX2 (0.42) | MAPTHPGDPKMGRIN2DGRIN3B | |
| SCHEMBL21002581 | 0.85 | GRIN2D (0.48) | MAPTPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6902613 | 0.83 | GRIN2D (0.59) | MAPTHPGDPKMGRIN2DGRIN3B | |
| SCHEMBL1712950 | 0.82 | MAPT (0.46) | MAPTHPGDPKMGRIN2DGRIN3B | |
| SCHEMBL6902836 | 0.82 | GRIN2D (0.37) | MAPTHPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL14695864 | 0.82 | GRIN2D (0.39) | MAPTHPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1712949 | 0.80 | MAPT (0.48) | MAPTHPGDPKMGRIN2DGRIN3B | |
| SCHEMBL14696231 | 0.80 | ALDH1A1 (0.42) | MAPTPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL17818867 | 0.80 | GRIN2D (0.59) | MAPTHPGDPKMGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051256-B1 | Process for producing hydroxy adamantane carboxylic acid compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-8481016-B2 | Method for inhibition of potential-dependent cation channel | KAO CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20130045177-A1 | Method for Inhibition of Potential-Dependent Cation Channel | KAO CORPORATION (JP) | 2013-02-21 | — | — | US | disclosed |
| EP-1258292-B1 | Oxidation catalytic system and oxidation process using same | DAICEL CHEM (JP) | 2004-05-19 | — | — | EP | disclosed |
| EP-0824962-B1 | USE OF AN OXIDATION CATALYST SYSTEM AND PROCESS FOR OXIDATION WITH THE SAME | DAICEL CHEM (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-0858835-B1 | Oxidation catalytic system and oxidation process | DAICEL CHEM (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1258292-A1 | Oxidation catalytic system and oxidation process using same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5981420-A | OXIDATION CATALYSTS SYSTEM CONSISTS OF AN N-HYDROXY OR N-OXY IMIDE COMPOUND AND A TRANSITION METAL COMPOUND EXCLUDING A POLYACID AS COCATALYST | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5958821-A | EPOXIDATION OF AN ALKENE USING A CYCLIC N-HYDROXYIMIDE AND A COCATALYST OF A COMPOUND OF A GROUP 2A OR TRANSITION METAL USING OXYGEN; CATALYST SELECTIVITY; FREE OF PHOSPHO-VANADOMOLYBDIC ACID OR TETRAPHENYLPORPHYRINTOATO MANGANESE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0858835-A1 | Oxidation catalytic system and oxidation process | Daicel Chemical Industries, Ltd. (JP) | 1998-08-19 | — | — | EP | disclosed |
| EP-0824962-A1 | OXIDATION CATALYST SYSTEM AND PROCESS FOR OXIDATION WITH THE SAME | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045177-A1 | Method for Inhibition of Potential-Dependent Cation Channel | TRPM7, TRPM8, OR10J3 | MAPT 4039/4885HPGD 1452/4885PKM 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.