SCHEMBL5609906

SCHEMBL5609906

COc1ccc(Br)c(C)c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
ERN1 O75460 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
ALDH1A1 P00352 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 2/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
TPMT P51580 1/20 0.43
CYP1A2 P05177 2/20 0.42
HPGD P15428 2/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825647 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL18857970 0.85 CYP3A4 (0.47) CA12CA1CA2CA7CA9
SCHEMBL29869353 0.85 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL11906262 0.84 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL31022830 0.84 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL3973107 0.84 ERN1 (0.45) CA12CA1CA2CA7CA9
SCHEMBL5610107 0.84 ERN1 (0.45) CA12CA1CA2CA7CA9
SCHEMBL7110575 0.82 CFD (0.49) ALDH1A1KDM4ECYP1A2HPGDCYP2C19
SCHEMBL2171213 0.81 ERN1 (0.54) CA12CA1CA2CA7CA9
SCHEMBL6953914 0.81 CA12 (0.55) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111943823-A Preparation method of metrafenone 安徽工业大学 2020-11-17 CN claimed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US claimed
CN-120349233-A Synthesis method of 3-bromo-6-methoxy-2-methylbenzoic acid 青岛科技大学 2025-07-22 CN disclosed
CN-120349233-A Synthesis method of 3-bromo-6-methoxy-2-methylbenzoic acid 青岛科技大学 2025-07-22 CN disclosed
CN-116375683-A Diazole derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2023-07-04 CN disclosed
EP-4114817-A1 A NOVEL FORM OF METRAFENONE, A PROCESS FOR ITS PREPARATION AND USE OF THE SAME Jiangsu Rotam Chemistry Co., Ltd (CN) 2023-01-11 EP disclosed
CN-115244027-A Novel forms of metrafenone, process for their preparation and their use 江苏龙灯化学有限公司 2022-10-25 CN disclosed
CN-111943823-A Preparation method of metrafenone 安徽工业大学 2020-11-17 CN disclosed
US-7253323-B2 Method for the production of benzophenones BASF AKTIENGESELLSCHAFT (DE) 2007-08-07 US disclosed
US-7253323-B2 Method for the production of benzophenones BASF AKTIENGESELLSCHAFT (DE) 2007-08-07 US disclosed
US-7253323-B2 Method for the production of benzophenones BASF AKTIENGESELLSCHAFT (DE) 2007-08-07 US disclosed
CN-1147456-C Fungicidal 2-methoxybenzophenones 2004-04-28 CN disclosed
EP-0897904-B1 Fungicidal 2-methoxybenzophenones BASF AG (DE) 2002-02-20 EP disclosed
US-20010031753-A1 Process for the preparation of substituted benzophenones BASF CORPORATION (US) 2001-10-18 US disclosed
WO-2001051440-A1 A PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZOPHENONES BASF AKTIENGESELLSCHAFT (DE) 2001-07-19 WO disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US disclosed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
CN-1217317-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID CO (US) 1999-05-26 CN disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031753-A1 Process for the preparation of substituted benzophenones CYP1A1, CYP2E1, CYP1B1 CA12 4020/4885CA1 2833/4885CA2 3194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.