SCHEMBL561013

SCHEMBL561013

CC(C)(C)OC(=O)N1CCC(CCCBr)CC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 10/20 0.54
FAAH O00519 1/20 0.53
HPGD P15428 1/20 0.50
KDM4E B2RXH2 1/20 0.49
PKM P14618 1/20 0.49
GLS O94925 1/20 0.48
RECQL P46063 1/20 0.48
EPHX1 P07099 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL949101 0.95 GPR119 (0.56) GPR119FAAHHPGDKDM4EPKM
SCHEMBL7692137 0.94 GPR119 (0.58) GPR119FAAHHPGDKDM4EPKM
SCHEMBL7420864 0.94 GPR119 (0.58) GPR119FAAHHPGDKDM4EPKM
SCHEMBL11980483 0.93 GPR119 (0.48) GPR119FAAHHPGDKDM4EPKM
SCHEMBL561360 0.90 HPGD (0.53) GPR119FAAHHPGDKDM4EPKM
SCHEMBL15085741 0.90 GPR119 (0.59) GPR119FAAHHPGDKDM4EPKM
SCHEMBL8151168 0.86 GPR119 (0.55) GPR119FAAHHPGDKDM4EPKM
SCHEMBL560636 0.86 GPR119 (0.55) GPR119FAAHHPGDKDM4EPKM
SCHEMBL5039032 0.85 GPR119 (0.47) GPR119FAAHHPGDKDM4EPKM
SCHEMBL8206 0.85 HPGD (0.54) GPR119FAAHHPGDKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108787-A FAPI modified by 4- (p-iodophenyl) butyric acid, nuclide marker, preparation method and application 核工业四一六医院 2024-05-31 CN claimed
EP-4676929-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2026-01-14 EP disclosed
WO-2025262295-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 EP disclosed
EP-4667466-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 EP disclosed
US-20250282771-A1 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS Treeline Biosciences, Inc. 2025-09-11 US disclosed
EP-4603488-A1 NOVEL INDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF Korea University Research and Business Foundation (KR) 2025-08-20 EP disclosed
WO-2025137500-A1 KINASE INHIBITION AND DEGRADATION DANA-FARBER CANCER INSTITUTE, INC. (US) 2025-06-26 WO disclosed
WO-2025101571-A1 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-X L DEGRADERS Treeline Biosciences, Inc. (US) 2025-05-15 WO disclosed
US-6020362-A ANTICOAGULANTS ELI LILLY AND COMPANY (US) 2000-02-01 US disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed
EP-0871442-A1 BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1998-10-21 EP disclosed
EP-0804431-A4 GLYCOPROTEIN IIb/IIIa ANTAGONISTS LILLY CO ELI (US) 1998-04-29 EP disclosed
US-5731324-A Glycoprotein IIb/IIIa antagonists ELI LILLY AND COMPANY (US) 1998-03-24 US disclosed
EP-0804431-A1 GLYCOPROTEIN IIb/IIIa ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-11-05 EP disclosed
WO-1997025041-A1 BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 1997-07-17 WO disclosed
US-5618843-A INHIBIT PLATELET AGGREGATION ELI LILLY AND COMPANY (US) 1997-04-08 US disclosed
WO-1996022288-A1 GLYCOPROTEIN IIb/IIIa ANTAGONISTS ELI LILLY AND COMPANY (US) 1996-07-25 WO disclosed
EP-0635492-A1 Glycoprotein IIb/IIIa antagonists ELI LILLY AND COMPANY (US) 1995-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282771-A1 TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS BCL2, BCL2L10, BCL2L1 GPR119 2666/4885FAAH 1738/4885HPGD 2424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.