Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047386 | 0.89 | ACE (0.50) | ACEPPARAPPARG | |
| SCHEMBL8658899 | 0.84 | ACE (0.63) | ACEPPARAPPARGPPARD | |
| SCHEMBL8658895 | 0.84 | ACE (0.63) | ACEPPARAPPARGPPARD | |
| SCHEMBL8997921 | 0.83 | ACE (0.62) | ACEPPARAPPARGPPARD | |
| SCHEMBL8997911 | 0.83 | ACE (0.62) | ACEPPARAPPARGPPARD | |
| SCHEMBL3963125 | 0.83 | ACE (0.58) | ACEPPARAPPARGPPARD | |
| SCHEMBL3963130 | 0.83 | ACE (0.58) | ACEPPARAPPARGPPARD | |
| SCHEMBL5217215 | 0.83 | ACE (0.62) | ACEPPARAPPARGPPARD | |
| SCHEMBL2240346 | 0.82 | ACE (0.57) | ACEPPARAPPARGPPARD | |
| Hydrochloric Acid SCHEMBL18260619 | 0.82 | ACE (0.57) | ACEPPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817324-A2 | SYNTHESES OF POLYAMINE CONJUGATES OF SMALL INTERFERING RNAS (SI-RNAS) AND CONJUGATES FORMED THEREBY | Andino, Raul (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006052854-A2 | SYNTHESES OF POLYAMINE CONJUGATES OF SMALL INTERFERING RNAS (SI-RNAS) AND CONJUGATES FORMED THEREBY | ANDINO RAUL (US) | 2006-05-18 | — | — | WO | disclosed |