Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.57 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347298 | 0.92 | PPARA (0.61) | ACEPPARAPPARG | |
| SCHEMBL3963130 | 0.89 | ACE (0.58) | ACEPPARAPPARGPPARD | |
| SCHEMBL3963125 | 0.89 | ACE (0.58) | ACEPPARAPPARGPPARD | |
| Hydrochloric Acid SCHEMBL18260619 | 0.87 | ACE (0.57) | ACEPPARAPPARGPPARD | |
| SCHEMBL14405000 | 0.86 | ACE (0.59) | ACEPPARAPPARGPPARD | |
| SCHEMBL9320401 | 0.83 | ANPEP (0.48) | — | |
| SCHEMBL2238427 | 0.83 | METAP2 (0.53) | ACEPPARAPPARG | |
| SCHEMBL8997911 | 0.82 | ACE (0.62) | ACEPPARAPPARGPPARD | |
| SCHEMBL5217215 | 0.82 | ACE (0.62) | ACEPPARAPPARGPPARD | |
| SCHEMBL8997921 | 0.82 | ACE (0.62) | ACEPPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231532-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2020-07-23 | — | — | US | claimed |
| US-20180099923-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2018-04-12 | — | — | US | claimed |
| EP-2536500-B1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2016-12-07 | — | — | EP | claimed |
| EP-2536500-A1 | SUPPORTED METAL CATALYSTS | Johnson Matthey PLC (GB) | 2012-12-26 | — | — | EP | claimed |
| CN-102834174-A | Supported metal catalysts | JOHNSON MATTHEY PLC | 2012-12-19 | — | — | CN | claimed |
| WO-2011101679-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2011-08-25 | — | — | WO | claimed |
| US-20200231532-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2020-07-23 | — | — | US | disclosed |
| US-20180099923-A1 | Supported Metal Catalysts | JOHNSON MATTHEY PLC (GB) | 2018-04-12 | — | — | US | disclosed |
| EP-2536500-B1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2016-12-07 | — | — | EP | disclosed |
| EP-2536500-A1 | SUPPORTED METAL CATALYSTS | Johnson Matthey PLC (GB) | 2012-12-26 | — | — | EP | disclosed |
| CN-102834174-A | Supported metal catalysts | JOHNSON MATTHEY PLC | 2012-12-19 | — | — | CN | disclosed |
| WO-2011101679-A1 | SUPPORTED METAL CATALYSTS | JOHNSON MATTHEY PLC (GB) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231532-A1 | Supported Metal Catalysts | SOD1, HNMT, SOD3 | ACE 914/4885PPARA 3524/4885PPARG 4398/4885 |
| US-20180099923-A1 | Supported Metal Catalysts | SOD1, HNMT, SOD3 | ACE 914/4885PPARA 3524/4885PPARG 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.