Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554787 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL28709863 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL3424708 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL11798444 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL11271581 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL7768831 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL10490506 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL1148737 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL11750658 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 | |
| SCHEMBL30164499 | 1.00 | GPR84 (0.63) | GPR84FFAR1CES2FFAR4CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589815-A4 | POLYCOSANOLS FROM i ERICERUS PELA /i WAX | UNIGEN PHARMACEUTICALS INC (US) | 2007-10-10 | — | — | EP | disclosed |
| US-7034060-B2 | Polycosanols from Ericerus pela wax | UNIGEN PHARMACEUTICALS, INC. (US) | 2006-04-25 | — | — | US | disclosed |
| US-6984666-B2 | Polycosanols from Ericerus pela wax | UNIGEN PHARMACEUTICALS, INC. (US) | 2006-01-10 | — | — | US | disclosed |
| EP-1589815-A2 | POLYCOSANOLS FROM i ERICERUS PELA /i WAX | Unigen Pharmaceuticals, Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20050239904-A1 | Polycosanols from Ericerus pela wax | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | US | disclosed |
| US-20050131078-A1 | Polycosanols from ericerus pela wax | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-06-16 | — | — | US | disclosed |
| US-20050124703-A1 | Polycosanols from Ericerus pela wax | UNIGEN PHARMACEUTICALS, INC (US) | 2005-06-09 | — | — | US | disclosed |
| US-6822004-B2 | PRIMARY ALIPHATIC C24-30 ALCOHOLS FROM THE WAX SECRETED BY THE INSECT ERICERUS PELA; TETRACOSANOL, HEXACOSANOL, OCTACOSANOL AND TRIACONTANOL; TREATMENT OF OBESITY, SYNDROME X, DIABETES, HYPERCHOLESTEROLEMIA, ISCHEMIA, THROMBOSIS, ATHEROSCLEROSIS | UNIGEN PHARMACEUTICALS, INC. | 2004-11-23 | — | — | US | disclosed |
| WO-2004069161-A2 | POLYCOSANOLS FROM ERICERUS PELA WAX | UNIGEN PHARMACEUTICALS, INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| US-20040152787-A1 | Polycosanols from ericerus pela wax | UNIGEN PHARMACEUTICALS, INC. | 2004-08-05 | — | — | US | disclosed |
| US-6683116-B1 | PRIMARILY COMPRISED OF TETRACOSANOL, HEXACOSANOL, OCTACOSANOL AND TRIACONTANOL; HYDROLYSIS AND NEUTRALIZATION; OBESITY, SYNDROME X, DIABETES, HYPERCHOLESTEROLEMIA, ATHEROSCLEROTIC COMPLICATIONS, ISCHEMIA, THROMBOSIS | UNIGEN PHARMACEUTICALS, INC. | 2004-01-27 | — | — | US | disclosed |