SCHEMBL5611229

SCHEMBL5611229

CCOC(=O)C=C(C(=O)OCC)C(CCl)CCCl

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.49
HCAR2 Q8TDS4 1/20 0.34
GLO1 Q04760 1/20 0.33
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5611226 1.00 NPSR1 (0.49) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL5611377 0.84 ATM (0.44) NPSR1HCAR2ALDH1A1
SCHEMBL5611374 0.84 ATM (0.44) NPSR1HCAR2ALDH1A1
SCHEMBL234358 0.75 NPSR1 (0.59) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL234359 0.75 NPSR1 (0.59) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL28432838 0.74 NPSR1 (0.57) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL28181558 0.72 NPSR1 (0.50) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL10725795 0.70 NPSR1 (0.52) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL28181560 0.70 NPSR1 (0.52) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL7450064 0.69 NPSR1 (0.54) NPSR1HCAR2GLO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed