SCHEMBL5611252

SCHEMBL5611252

CC(C)COC(=O)C(Cl)(Cl)C(=O)OCC(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PRKCA P17252 1/20 0.35
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
RAB9A P51151 1/20 0.33
P2RX4 Q99571 1/20 0.33
MMP8 P22894 1/20 0.32
MAPK1 P28482 2/20 0.32
GAA P10253 1/20 0.32
NR1H3 Q13133 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11341798 0.86 TSHR (0.45) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL26357271 0.84 TSHR (0.43) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL7763970 0.82 TSHR (0.42) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL5611231 0.82 TSHR (0.42) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL11856582 0.79 TSHR (0.39) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL8649631 0.79 TSHR (0.39) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL1785988 0.78 TSHR (0.46) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL7945587 0.78 TSHR (0.46) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL685935 0.78 PRKCA (0.55) TSHRALDH1A1TDP1L3MBTL1PRKCA
SCHEMBL1164845 0.77 TSHR (0.42) TSHRALDH1A1TDP1L3MBTL1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
CN-103764690-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2016-12-14 CN disclosed
US-20140206827-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-07-24 US disclosed
CN-103764690-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2014-04-30 CN disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed
EP-0687665-A1 Process for preparing 2,2-dichloro-malonic acid esters HÜLS AKTIENGESELLSCHAFT (DE) 1995-12-20 EP disclosed