SCHEMBL5611368

SCHEMBL5611368

CCCC(C(=O)O)=C(CC)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 4/20 0.48
HDAC3 O15379 4/20 0.48
HDAC1 Q13547 4/20 0.48
HDAC2 Q92769 4/20 0.48
HDAC8 Q9BY41 4/20 0.48
ALDH1A1 P00352 3/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
THRB P10828 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
PGGT1B P53609 1/20 0.41
TSHR P16473 4/20 0.39
AKR1B1 P15121 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
GRIK1 P39086 1/20 0.35
GRIA4 P48058 1/20 0.35
GRIK3 Q13003 1/20 0.35
GRIK5 Q16478 1/20 0.35
PPARG P37231 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107841 1.00 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL5611361 1.00 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL554603 0.91 HDAC3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL554602 0.91 HDAC3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL184432 0.91 HDAC3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL305222 0.88 HDAC3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL305220 0.88 HDAC3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL101165 0.85 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL42601 0.85 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL42603 0.85 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210319-B1 IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE BAYER AG (US) 2003-11-05 EP claimed
EP-1208135-B1 IN-SITU PREPARATION OF POLYASPARTIC ESTER MIXTURE BAYER AG (US) 2003-10-01 EP claimed
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
US-11548980-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2023-01-10 US disclosed
US-20210139645-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-05-13 US disclosed
EP-3625283-A1 POLYESTER COPOLYMER Avantium Knowledge Centre B.V. (NL) 2020-03-25 EP disclosed
WO-2018211132-A1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2018-11-22 WO disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed