Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058350 | 1.00 | OPRD1 (0.55) | OPRD1OPRM1STAT6 | |
| Trifluoroacetic Acid SCHEMBL29706375 | 0.97 | OPRD1 (0.52) | OPRD1OPRM1STAT6 | |
| Trifluoroacetic Acid SCHEMBL28184395 | 0.97 | OPRD1 (0.52) | OPRD1OPRM1STAT6 | |
| SCHEMBL29509580 | 0.91 | OPRD1 (0.59) | OPRD1OPRM1 | |
| SCHEMBL29376540 | 0.89 | OPRD1 (0.61) | OPRD1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL29509617 | 0.86 | OPRD1 (0.58) | OPRD1OPRM1 | |
| SCHEMBL29462069 | 0.84 | OPRD1 (0.65) | OPRD1OPRM1 | |
| SCHEMBL28184393 | 0.83 | OPRD1 (0.49) | OPRD1OPRM1STAT6 | |
| SCHEMBL30832772 | 0.79 | OPRD1 (0.61) | OPRD1OPRM1 | |
| SCHEMBL5489858 | 0.78 | ACE (0.51) | OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799243-A2 | TREATMENT OF PULMONARY HYPERTENSION USING AN AGENT THAT INHIBITS A TISSUE FACTOR PATHWAY | UNIVERSITY OF ROCHESTER (US) | 2007-06-27 | — | — | EP | claimed |
| WO-2006042017-A2 | TREATMENT OF PULMONARY HYPERTENSION USING AN AGENT THAT INHIBITS A TISSUE FACTOR PATHWAY | UNIVERSITY OF ROCHESTER (US) | 2006-04-20 | — | — | WO | claimed |
| EP-1799243-A2 | TREATMENT OF PULMONARY HYPERTENSION USING AN AGENT THAT INHIBITS A TISSUE FACTOR PATHWAY | UNIVERSITY OF ROCHESTER (US) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006042017-A2 | TREATMENT OF PULMONARY HYPERTENSION USING AN AGENT THAT INHIBITS A TISSUE FACTOR PATHWAY | UNIVERSITY OF ROCHESTER (US) | 2006-04-20 | — | — | WO | disclosed |