SCHEMBL561272

SCHEMBL561272

CCCCCCCC(C)[Si]

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
SPHK1 Q9NYA1 1/20 0.46
LMNA P02545 1/20 0.46
DNM1 Q05193 2/20 0.46
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH4 P08319 1/20 0.43
ADH7 P40394 1/20 0.43
ACE2 Q9BYF1 1/20 0.41
GPR84 Q9NQS5 3/20 0.41
FDPS P14324 3/20 0.41
FFAR1 O14842 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8151058 0.97
SCHEMBL21086628 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL20506768 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL20506756 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL20506761 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA
Hexadecane SCHEMBL23000686 0.75 OPRM1 (0.55) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL20506755 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL22950680 0.75 OPRM1 (0.55) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL20835139 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA
SCHEMBL20506759 0.75 ACE2 (0.62) OPRM1TSHRTHRBSPHK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9475010-B2 Porous membranes made up of organopolysiloxane copolymers WACKER CHEMIE AG (DE) 2016-10-25 US disclosed
US-20160001237-A1 ASYMMETRICALLY POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2016-01-07 US disclosed
US-20150376365-A1 POROUS MEMBRANES MADE OF CROSS-LINKED THERMOPLASTIC SILICONE ELASTOMER WACKER CHEMIE AG (DE) 2015-12-31 US disclosed
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US disclosed
US-20120296062-A1 METHOD FOR PRODUCING POROUS SILICON MOLDED BODIES WACKER CHEMIE AG (DE) 2012-11-22 US disclosed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US disclosed
US-20110127219-A1 POROUS MEMBRANES MADE UP OF ORGANOPOLYSILOXANE COPOLYMERS WACKER CHEMIE AG (DE) 2011-06-02 US disclosed