Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL408155 | 0.84 | TP53 (0.39) | TSHR | |
| Sulfuric Acid SCHEMBL8715917 | 0.84 | TP53 (0.39) | TSHR | |
| Sulfamate SCHEMBL1736409 | 0.83 | — | — | |
| Sulfamate SCHEMBL29501507 | 0.79 | TSHR (0.46) | CA1CA2CA7CA4CA6 | |
| Sulfamate SCHEMBL15516480 | 0.78 | CA2 (0.56) | CA1CA2CA7CA4CA6 | |
| Lithium Ion SCHEMBL7634828 | 0.77 | — | — | |
| Sulfuric Acid SCHEMBL2513387 | 0.75 | TP53 (0.39) | TSHR | |
| Sulfamide SCHEMBL16550649 | 0.75 | CA1 (0.55) | CA1CA2CA7CA4CA6 | |
| Sulfuric Acid SCHEMBL31171296 | 0.75 | MEN1 (0.43) | TSHR | |
| Sulfuric Acid SCHEMBL3208262 | 0.75 | TP53 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135310-B1 | CELL STRUCTURE FOR ELECTROCHEMICAL DEVICES AND METHOD OF MAKING SAME | INVENTEK CORP (US) | 2016-04-20 | — | — | EP | disclosed |
| US-8734983-B2 | Housing for electrochemical devices | INVENTEK CORPORATION (US) | 2014-05-27 | — | — | US | disclosed |
| US-8263248-B2 | Cell structure for electrochemical devices and method of making same | INVENTEK CORPORATION (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120034500-A1 | CELL STRUCTURE FOR ELECTROCHEMICAL DEVICES AND METHOD OF MAKING SAME | INVENTEK CORPORATION (US) | 2012-02-09 | — | — | US | disclosed |
| US-8021775-B2 | Cell structure for electrochemical devices and method of making same | INVENTEK CORPORATION (US) | 2011-09-20 | — | — | US | disclosed |
| EP-2135310-A1 | CELL STRUCTURE FOR ELECTROCHEMICAL DEVICES AND METHOD OF MAKING SAME | Kaun, Thomas D. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008109025-A1 | CELL STRUCTURE FOR ELECTROCHEMICAL DEVICES AND METHOD OF MAKING SAME | KAUN THOMAS D (US) | 2008-09-12 | — | — | WO | disclosed |
| US-20070160901-A1 | Cell structure for electrochemical devices and method of making same | INVENTEX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-7195840-B2 | Cell structure for electrochemical devices and method of making same | INVENTEK CORPORATION | 2007-03-27 | — | — | US | disclosed |
| US-20050233212-A1 | Housing for electrochemical devices | INVENTEK CORPORATION | 2005-10-20 | — | — | US | disclosed |
| US-20030013007-A1 | Inexpensive system that utilizes solid catholytes such as oxides, peroxides and superoxides of alkaline metals in which the rate of hydrolysis is controlled to limit the production of cathode species (hydrogen peroxid) to the rate at which they are consumed in the semi fuel cell; submarine batteries | INVENTEK CORPORATION | 2003-01-16 | — | — | US | disclosed |