Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | EIF4E | P06730 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TOP1 | P11387 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | ADK | P55263 | 8/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754419 | 1.00 | PNP (0.75) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL15019632 | 1.00 | PNP (0.75) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL12149488 | 0.85 | LMNA (0.75) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL12149489 | 0.85 | LMNA (0.75) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL15253047 | 0.83 | LMNA (0.67) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL14108533 | 0.82 | LMNA (0.79) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL15019611 | 0.82 | LMNA (0.79) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL12150452 | 0.82 | LMNA (0.79) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL12149570 | 0.82 | LMNA (0.63) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 | |
| Ribavirin SCHEMBL4064991 | 0.81 | LMNA (1.00) | PNPLMNASMN1; SMN2ADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070134255-A1 | Hmpv treatment with ribavirin and anti-hmpv antibody | VIRONOVATIVE B.V. (NL) | 2007-06-14 | — | — | US | disclosed |
| WO-2004096241-A1 | HMPV TREATMENT WITH RIBAVIRIN AND ANTI-HMPV ANTIBODY | VIRONOVATIVE B.V. (NL) | 2004-11-11 | — | — | WO | disclosed |
| EP-1244356-A4 | COMPOSITIONS AND METHODS FOR L-NUCLEOSIDES, L-NUCLEOTIDES, AND THEIR ANALOGS | ICN PHARMACEUTICALS (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1244356-A1 | COMPOSITIONS AND METHODS FOR L-NUCLEOSIDES, L-NUCLEOTIDES, AND THEIR ANALOGS | ICN Pharmaceuticals, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001045642-A2 | PULMONARY DELIVERY OF RIBAVIRIN OR LEVOVIRIN™ FOR SYSTEMIC AND QUASI-SYSTEMIC TREATMENT OF DISEASE | ICN PHARMACEUTICALS, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001045509-A1 | COMPOSITIONS AND METHODS FOR L-NUCLEOSIDES, L-NUCLEOTIDES, AND THEIR ANALOGS | ICN PHARMACEUTICALS, INC. (US) | 2001-06-28 | — | — | WO | disclosed |