Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.89 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.89 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.89 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.89 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.89 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.89 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.89 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.89 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.89 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.68 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.64 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563043 | 1.00 | P2RX3 (0.89) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL30181339 | 1.00 | P2RX3 (0.89) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL5847070 | 0.97 | P2RX3 (0.91) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL29381827 | 0.94 | ENPP1 (1.00) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL19248226 | 0.94 | ENPP1 (1.00) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL1441797 | 0.94 | ENPP1 (1.00) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL3682844 | 0.94 | ENPP1 (1.00) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL19255493 | 0.94 | ENPP1 (1.00) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL29810828 | 0.93 | ENPP1 (0.99) | P2RX3P2RX2P2RX4P2RX1P2RY11 | |
| SCHEMBL5848925 | 0.91 | ENPP1 (0.94) | P2RX3P2RX2P2RX4P2RX1P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020018-A1 | USE OF PURINERGIC AND PYRIMIDINERGIC RECEPTOR AGONISTS FOR DENDRITIC CELLS BASED IMMUNOTHERAPIES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2003028712-A2 | PURINERGIC AND PYRIMIDINERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF ACTIVATED CD4+ T LYMPHOCYTE-MEDIATED IMMUNE DISEASES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2003-04-10 | — | — | WO | disclosed |