⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468728 | 0.82 | — | — | |
| SCHEMBL619312 | 0.79 | TDP1 (0.69) | — | |
| SCHEMBL27750325 | 0.79 | — | — | |
| SCHEMBL95885 | 0.78 | — | — | |
| Hydrogen Sulfide SCHEMBL29291893 | 0.76 | TDP1 (0.64) | — | |
| SCHEMBL30255411 | 0.76 | TDP1 (0.64) | — | |
| SCHEMBL13379743 | 0.76 | TDP1 (0.64) | — | |
| SCHEMBL8984748 | 0.76 | TDP1 (0.64) | — | |
| SCHEMBL8371300 | 0.76 | TDP1 (0.64) | — | |
| SCHEMBL31384133 | 0.76 | ACE (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129116-A1 | CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS | UNIVERSITY OF SOUTH CAROLINA | 2025-04-24 | — | — | US | claimed |
| US-20260118361-A1 | FLUOROGENIC BIOCONJUGATION OF CYCLOPROPANOL-BASED FLUOROPHORES FOR BIOLOGICAL APPLICATIONS | UNIV SOUTH CAROLINA (US) | 2026-04-30 | — | — | US | disclosed |
| US-20250129116-A1 | CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS | UNIVERSITY OF SOUTH CAROLINA | 2025-04-24 | — | — | US | disclosed |
| US-20200407321-A1 | HIGH-YIELDING CONTINUOUS FLOW SYNTHESIS OF ANTIMALARIAL DRUG HYDROXYCHLOROQUINE | VIRGINIA COMMONWEALTH UNIVERSITY | 2020-12-31 | — | — | US | disclosed |
| WO-2019165337-A1 | HIGH-YIELDING CONTINUOUS FLOW SYNTHESIS OF ANTIMALARIAL DRUG HYDROXYCHLOROQUINE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2019-08-29 | — | — | WO | disclosed |
| US-20070270521-A1 | Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-11-22 | — | — | US | disclosed |