Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 10/20 | 0.73 |
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.66 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473366 | 0.85 | IMPDH2 (1.00) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1476067 | 0.85 | IMPDH2 (0.79) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5524840 | 0.83 | IMPDH2 (0.73) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6484130 | 0.83 | IMPDH2 (0.74) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL15741817 | 0.82 | AAK1 (0.80) | IMPDH2AAK1 | |
| SCHEMBL5613894 | 0.81 | IMPDH2 (0.73) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL3939748 | 0.81 | IMPDH2 (0.83) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL14518602 | 0.81 | IMPDH2 (0.83) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6485198 | 0.80 | IMPDH2 (0.64) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL3995894 | 0.80 | IMPDH2 (0.82) | IMPDH2AAK1IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786415-A1 | METABOLISM-MODULATING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006017896-A1 | METABOLISM-MODULATING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-02-23 | — | — | WO | disclosed |