Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 14/20 | 0.68 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.58 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239482 | 0.99 | IMPDH2 (0.67) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1475380 | 0.93 | IMPDH2 (0.66) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1475381 | 0.93 | IMPDH2 (0.66) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1475383 | 0.93 | IMPDH2 (0.66) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5530894 | 0.88 | IMPDH2 (0.70) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5529110 | 0.85 | IMPDH2 (0.69) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL16239527 | 0.85 | IMPDH2 (0.63) | IMPDH2AAK1 | |
| SCHEMBL5526296 | 0.84 | IMPDH2 (0.63) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5524973 | 0.84 | AAK1 (0.65) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5531758 | 0.83 | AAK1 (0.66) | IMPDH2AAK1IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2803357-B1 | Angiogenesis inhibitors | UNIV JOHNS HOPKINS (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-2803357-A2 | Angiogenesis inhibitors | THE JOHNS-HOPKINS UNIVERSITY (US) | 2014-11-19 | — | — | EP | disclosed |
| EP-1786415-A1 | METABOLISM-MODULATING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006017896-A1 | METABOLISM-MODULATING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-02-23 | — | — | WO | disclosed |