⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15609706 | 0.88 | — | — | |
| SCHEMBL15609707 | 0.88 | — | — | |
| SCHEMBL28317214 | 0.88 | — | — | |
| SCHEMBL12543858 | 0.82 | — | — | |
| SCHEMBL7515390 | 0.78 | — | — | |
| SCHEMBL16885286 | 0.78 | SLC6A4 (0.30) | — | |
| SCHEMBL18798964 | 0.77 | — | — | |
| SCHEMBL1129505 | 0.76 | CYP2C19 (0.31) | — | |
| SCHEMBL20187413 | 0.76 | — | — | |
| SCHEMBL339400 | 0.75 | OPRM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242984-B2 | Pyrazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150191461-A1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-07-09 | — | — | US | disclosed |
| WO-2007037540-A1 | CELLULOSE ACYLATE FILM, METHOD FOR PRODUCING SAME, OPTICALLY COMPENSATORY FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |
| US-4266026-A | Catalytic process utilizing hollow fiber membranes | ROHM AND HAAS COMPANY (US) | 1981-05-05 | — | — | US | disclosed |