SCHEMBL5614352

SCHEMBL5614352

CCCCCCCC[Zr](C)([SiH3])(Cl)(Cl)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.41
BCHE P06276 1/20 0.41
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7627814 0.80 ACHE (0.44) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL6447626 0.69 POLB (0.32) ACHEBCHECHRM2HTR1AADRA2A
SCHEMBL6061312 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL6060774 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL6060761 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL6061696 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL407781 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL1449246 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL6060915 0.68 HTR2A (0.54) ACHEBCHE
SCHEMBL6060938 0.68 HTR2A (0.54) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773897-A2 IMPROVED ACIDIC ACTIVATOR-SUPPORTS AND CATALYSTS FOR OLEFIN POLYMERIZATION Chevron Phillips Chemical Company LP (US) 2007-04-18 EP disclosed
WO-2006012321-A2 IMPROVED ACIDIC ACTIVATOR-SUPPORTS AND CATALYSTS FOR OLEFIN POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-02-02 WO disclosed