⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987840 | 0.65 | — | — | |
| SCHEMBL17273531 | 0.64 | — | — | |
| SCHEMBL8913616 | 0.63 | — | — | |
| SCHEMBL3835888 | 0.63 | HSP90AA1 (0.31) | — | |
| SCHEMBL536971 | 0.60 | LRRK2 (0.31) | — | |
| SCHEMBL28151351 | 0.59 | — | — | |
| SCHEMBL127479 | 0.58 | EGFR (0.50) | — | |
| SCHEMBL28003243 | 0.56 | EGFR (0.48) | — | |
| SCHEMBL15386176 | 0.55 | CDC25B (0.41) | — | |
| SCHEMBL4860463 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107490-A1 | HETEROCYCLE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS | PRETZEL THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | claimed |
| US-11566042-B2 | Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds | ZATA Pharmaceuticals, Inc (US) | 2023-01-31 | — | — | US | claimed |
| US-20210347645-A1 | Macroporous Controlled Porosity Silica Gel Suitable For Oligonucleotide Synthesis | CHEMGENES CORPORATION | 2021-11-11 | — | — | US | claimed |
| EP-3906997-A2 | MACROPOROUS CONTROLLED POROSITY SILICA GEL SUITABLE FOR OLIGONUCLEOTIDE SYNTHESIS | Chemgenes Corporation (US) | 2021-11-10 | — | — | EP | claimed |
| US-11078227-B2 | 5′-cyclo-phosphonate modified nucleotides | Arrowhead Pharmaceuticals, Inc. (US) | 2021-08-03 | — | — | US | claimed |
| US-10723755-B2 | Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds | ZATA PHARMACEUTICALS, INC. (US) | 2020-07-28 | — | — | US | claimed |
| US-8618279-B2 | Synthesis of 2′,3′— and 3′,5′—cyclic phosphate mono-and oligonucleotides | CHEMGENES CORPORATION (US) | 2013-12-31 | — | — | US | claimed |
| US-8153779-B2 | Nucleotide with an alpha-phosphate mimetic | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-04-10 | — | — | US | claimed |
| US-20120034184-A1 | 4'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF HCV RNA REPLICATION | DEVOS RENE ROBERT (GB) | 2012-02-09 | — | — | US | claimed |
| JP-2007512358-A | — | — | 2007-05-17 | — | — | JP | claimed |
| EP-0863757-A1 | 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 1998-09-16 | — | — | EP | claimed |
| EP-0859771-A1 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 1998-08-26 | — | — | EP | claimed |
| WO-1997016441-A1 | SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | claimed |
| WO-1997016442-A1 | SUBSTITUTED PYRIDYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | claimed |
| WO-1997016426-A1 | SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | claimed |
| WO-1997005878-A1 | 2,5-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | claimed |
| WO-1997005877-A1 | 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-02-20 | — | — | WO | claimed |
| EP-0719274-A1 | METHOD FOR DOSING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1996-07-03 | — | — | EP | claimed |
| WO-1995007919-A1 | METHOD FOR DOSING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1995-03-23 | — | — | WO | claimed |
| EP-0340778-A2 | Prodrugs of 2',3'- Didehydro-2',3'-Dideoxynucleosides | Bristol-Myers Squibb Company (US) | 1989-11-08 | — | — | EP | claimed |