Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615321 | 0.97 | SMN1; SMN2 (0.43) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL8721095 | 0.95 | KMT2A (0.40) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL5615504 | 0.91 | AHR (0.38) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL3918033 | 0.90 | MAPT (0.38) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL3922633 | 0.90 | KMT2A (0.38) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL2400659 | 0.89 | KDM4E (0.38) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL5182208 | 0.88 | MAPT (0.37) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL4146942 | 0.88 | MAPT (0.37) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL3163518 | 0.88 | MAPT (0.37) | ALDH1A1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL29613249 | 0.88 | MAPT (0.37) | ALDH1A1MAPTKMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | claimed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | claimed |
| US-9937434-B2 | Photochromic toy | THE PILOT INK CO., LTD. (JP) | 2018-04-10 | — | — | US | disclosed |
| US-20140141689-A1 | PHOTOCHROMIC TOY | THE PILOT INK CO., LTD. (JP) | 2014-05-22 | — | — | US | disclosed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | disclosed |
| EP-0713486-B1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 2002-07-17 | — | — | EP | disclosed |
| US-6312811-B1 | Photochromic naphtho [2,1-b]pyran compounds containing bithienyl or terthienyl substituents, process for their manufacture, and photochromic materials and articles obtained | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-11-06 | — | — | US | disclosed |
| US-6256152-B1 | Laminate wafers | SOLA INTERNATIONAL HOLDINGS LTD. (AU) | 2001-07-03 | — | — | US | disclosed |
| US-6175450-B1 | Transparent photochromic article including an anti-reflection surface coating | SOLA INTERNATIONAL HOLDING LTD (AU) | 2001-01-16 | — | — | US | disclosed |
| EP-0877962-A4 | LAMINATE WAFERS | SOLA INT HOLDINGS (AU) | 2000-03-22 | — | — | EP | disclosed |
| WO-1997028467-A1 | TRANSPARENT PHOTOCHROMIC ARTICLE INCLUDING AN ANTI-REFLECTION SURFACE COATING | SOLA INTERNATIONAL HOLDINGS LTD. (AU) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997022894-A1 | LAMINATE WAFERS | SOLA INTERNATIONAL HOLDINGS LTD. (AU) | 1997-06-26 | — | — | WO | disclosed |
| US-5623005-A | NAPTHOPYRAN COMPOUNDS CONTAINING AMINE SUBSTITUTION AT 6-POSITION; USEFUL TO MAKE OPHTHALMIC LENS | PILKINGTON PLC (GB) | 1997-04-22 | — | — | US | disclosed |
| EP-0691965-B1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-12-04 | — | — | EP | disclosed |
| EP-0713486-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1996-05-29 | — | — | EP | disclosed |
| US-5520853-A | LIGHT SENSITIVE COMPOUNDS FOR POLYMERS OR CELLULOSE DERIVATIVES FOR LENSES | PILKINGTON PLC (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0691965-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1996-01-17 | — | — | EP | disclosed |
| WO-1995005371-A1 | PHOTOCHROMIC NAPHTHO(2,1-B)PYRANS | PILKINGTON PLC (GB) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994022850-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PILKINGTON PLC (GB) | 1994-10-13 | — | — | WO | disclosed |