Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182208 | 1.00 | MAPT (0.37) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3929015 | 0.96 | HTT (0.39) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4146942 | 0.89 | MAPT (0.37) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5615531 | 0.88 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5615321 | 0.85 | SMN1; SMN2 (0.43) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3918033 | 0.85 | MAPT (0.38) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2400659 | 0.84 | KDM4E (0.38) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8721095 | 0.83 | KMT2A (0.40) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2398864 | 0.82 | MAPT (0.34) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8410549 | 0.81 | KDM4E (0.36) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466913-B | Dihydro quinoline photochromic compounds | 光学转变有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | disclosed |