Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616361 | 0.87 | MCHR1 (0.42) | MCHR1NPBWR1GAAHRH2HRH1 | |
| SCHEMBL4733671 | 0.86 | IRAK4 (0.41) | MCHR1NPBWR1RXFP1GAAHRH2 | |
| SCHEMBL4733667 | 0.83 | MCHR1 (0.40) | MCHR1NPBWR1GAAHRH2HRH1 | |
| Hydrochloric Acid SCHEMBL4731442 | 0.82 | NPBWR1 (0.44) | MCHR1NPBWR1GAAHRH2HRH1 | |
| SCHEMBL12540937 | 0.82 | IRAK4 (0.37) | MCHR1NPBWR1GAAHRH2HRH1 | |
| SCHEMBL12540936 | 0.82 | BRD4 (0.37) | MCHR1NPBWR1GAAHRH2HRH1 | |
| SCHEMBL12678422 | 0.82 | IRAK4 (0.38) | MCHR1NPBWR1GAAHRH2HRH1 | |
| SCHEMBL12540934 | 0.81 | CTSA (0.39) | MCHR1NPBWR1RXFP1GAAHRH2 | |
| SCHEMBL4732368 | 0.78 | MCHR1 (0.41) | MCHR1NPBWR1HRH3CTSAEGLN1 | |
| SCHEMBL4731667 | 0.77 | CD274 (0.43) | MCHR1CTSACD274IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089669-A2 | PROCESSES FOR THE PREPARATION OF COMPOUNDS WHICH MODULATE CELL PROLIFERATION | WYETH (US) | 2007-08-09 | — | — | WO | disclosed |