Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 6/20 | 0.31 |
| ▸ | RAB9A | P51151 | 6/20 | 0.31 |
| ▸ | HTT | P42858 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039410 | 0.97 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL6414746 | 0.97 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL27593365 | 0.97 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL8329170 | 0.97 | TP53 (0.37) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL269446 | 0.92 | — | — | |
| SCHEMBL20465806 | 0.85 | TP53 (0.48) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL27458343 | 0.82 | TP53 (0.46) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL72436 | 0.79 | — | — | |
| SCHEMBL691481 | 0.78 | TP53 (0.48) | TP53TBXAS1NPC1RAB9AHTT | |
| SCHEMBL7529371 | 0.72 | TP53 (0.39) | TP53TBXAS1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856164-A1 | SUPPORTED OLEFIN POLYMERIZATION CATALYSTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006094302-A1 | SUPPORTED OLEFIN POLYMERIZATION CATALYSTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-20060199727-A1 | Supported olefin polymerization catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-09-07 | — | — | US | disclosed |
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |
| EP-0867431-B1 | Process for the preparation of azide derivatives | EISAI CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6284317-B1 | PROVIDING SURFACE COMPRISING UNITS HAVING SILION-HYDROGEN BONDS; EXPOSING TO ORGANOMETALLIC REAGENT; FORMING A SILICON-CARBON BOND AT A TEMPERATURE OF LESS THAN ABOUT 25.DEGREE. C. AND FREE OF AN EXTERNAL ENERGY SOURCE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-09-04 | — | — | US | disclosed |
| US-5986088-A | Process for the preparation of azide derivatives | EISAI CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0867431-A1 | Process for the preparation of azide derivatives | Eisai Chemical Co., Ltd. (JP) | 1998-09-30 | — | — | EP | disclosed |