⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269446 | 0.81 | — | — | |
| SCHEMBL5616893 | 0.79 | TP53 (0.39) | — | |
| SCHEMBL27910344 | 0.78 | TP53 (0.53) | — | |
| SCHEMBL6414746 | 0.77 | TP53 (0.37) | — | |
| SCHEMBL27593365 | 0.77 | TP53 (0.37) | — | |
| SCHEMBL7039410 | 0.77 | TP53 (0.37) | — | |
| SCHEMBL8329170 | 0.77 | TP53 (0.37) | — | |
| SCHEMBL68671 | 0.72 | — | — | |
| SCHEMBL20465806 | 0.72 | TP53 (0.48) | — | |
| SCHEMBL691481 | 0.72 | TP53 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210316288-A1 | HYBRID MATERIAL AND METHOD FOR THE PRODUCTION THEREOF | UNIVERSITE PIERRE ET MARIE CURIE (FR) | 2021-10-14 | — | — | US | claimed |
| CN-110590708-B | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2021-08-17 | — | — | CN | claimed |
| CN-110590708-A | Aroyl piperazine compound, preparation method thereof and application thereof in antivirus | 中国医学科学院医药生物技术研究所 | 2019-12-20 | — | — | CN | claimed |
| US-RE46417-E1 | Quinuclidine derivatives and their use as muscarinic M3 receptor ligands | ALMIRALL, S.A. (ES) | 2017-05-30 | — | — | US | claimed |
| EP-1200431-B3 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTORS LIGANDS | ALMIRALL SA (ES) | 2015-06-24 | — | — | EP | claimed |
| CN-102924558-A | Betulinic acid esters derivative and preparation method and use of betulinic acid esters derivative | UNIV GUIZHOU | 2013-02-13 | — | — | CN | claimed |
| CN-102875633-A | Betulonic acid ester derivative and preparation method and application thereof | UNIV GUIZHOU | 2013-01-16 | — | — | CN | claimed |
| CN-102875632-A | Ursolic acid ester derivatives and preparation methods and applications thereof | UNIV GUIZHOU | 2013-01-16 | — | — | CN | claimed |
| US-20120321565-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 17ALPHA-FURANYLESTERS OF 17BETA-CARBOTHIATE ANDROSTANES WITH A MUSCARINIC RECEPTOR ANTAGONIST | GLAXOSMITHKLINE INTELLECTUAL PROPERTY MANAGEMENT LIMITED (GB) | 2012-12-20 | — | — | US | claimed |
| EP-2515657-A1 | TYROSINE KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-10-31 | — | — | EP | claimed |
| US-6482801-B2 | THERAPY FOR BACTERIAL OR PROTOZOA INFECTIONS | PFIZER INC. | 2002-11-19 | — | — | US | claimed |
| EP-1200431-A2 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR LIGANDS | Almirall Prodesfarma, S.A. (ES) | 2002-05-02 | — | — | EP | claimed |
| US-20010016574-A1 | 9a,11b-dehydro derivatives of 9-oxime-3-keto-6-O- methylerythromycin | WU YONG-JIN (US) | 2001-08-23 | — | — | US | claimed |
| US-6248719-B1 | Tricyclic 3-keto derivatives of 6-O-methylerthromycin | PFIZER INC | 2001-06-19 | — | — | US | claimed |
| WO-2001004118-A2 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR LIGANDS | ALMIRALL PRODESFARMA S.A. (ES) | 2001-01-18 | — | — | WO | claimed |
| WO-1999062920-A1 | TRICYCLIC 3-KETO DERIVATIVES OF 6-O-METHYLERYTHROMYCIN | PFIZER PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | claimed |
| EP-0952157-A1 | 9A, 11B-Dehydro derivatives of 9-oxime-3-keto-6-0-methylerythromycin | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| EP-0832898-A2 | Substituted amino acid derivatives | BAYER AG (DE) | 1998-04-01 | — | — | EP | claimed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | claimed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | claimed |