Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359396 | 0.86 | DDB1 (0.60) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL19359463 | 0.84 | DDB1 (0.58) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL4936560 | 0.84 | DDB1 (0.58) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL19359289 | 0.84 | DDB1 (0.58) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL12041909 | 0.84 | DDB1 (0.53) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL17873805 | 0.84 | DDB1 (0.60) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL4119644 | 0.82 | CASP3 (0.49) | DDB1CRBNKMT2AALDH1A1POLB | |
| SCHEMBL4937839 | 0.82 | DDB1 (0.55) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL21402722 | 0.81 | DDB1 (0.54) | DDB1CRBNMEN1KMT2AACHE | |
| SCHEMBL19359460 | 0.81 | DDB1 (0.64) | DDB1CRBNMEN1KMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076365-A2 | METHODS FOR DIAGNOSING AND TREATING A MYCOBACTERIUM AVIUM SUBSPECIES PARATUBERCULOSIS INFECTION | GREENSTEIN ROBERT J (US) | 2007-07-05 | — | — | WO | disclosed |