Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18726609 | 0.68 | GAA (0.34) | GAAMAPTGFERPEPDNPC1 | |
| SCHEMBL30398963 | 0.65 | GAA (0.32) | GAAMAPTGFERPEPDNPC1 | |
| SCHEMBL28483958 | 0.60 | — | — | |
| SCHEMBL28816279 | 0.60 | — | — | |
| SCHEMBL30047240 | 0.57 | — | — | |
| SCHEMBL3928666 | 0.54 | GAA (0.67) | GAAMAPTGFERPEPDNPC1 | |
| SCHEMBL29840068 | 0.54 | GAA (0.67) | GAAMAPTGFERPEPDNPC1 | |
| SCHEMBL5062623 | 0.54 | PEPD (0.80) | GAAMAPTGFERPEPDNPC1 | |
| SCHEMBL1787750 | 0.54 | PEPD (0.56) | GAAMAPTGFERPEPDNPC1 | |
| SCHEMBL7417077 | 0.53 | GAA (0.57) | GAAMAPTGFERPEPDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157457-B2 | Compounds useful in the treatment of inflammatory diseases | GLAXO GROUP LIMITED (GB) | 2007-01-02 | — | — | US | disclosed |