SCHEMBL1787750

SCHEMBL1787750

NC(=O)Nc1cc(NC(N)=O)cc(NC(N)=O)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PEPD P12955 1/20 0.56
ALDH1A1 P00352 3/20 0.54
NPC1 O15118 1/20 0.54
MAPT P10636 2/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
KIF11 P52732 7/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48
GLA P06280 1/20 0.43
HSD17B10 Q99714 2/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11445693 0.89 PEPD (0.48) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL8698243 0.87 PEPD (0.46) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL3690365 0.84 MAPT (0.59) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL5523767 0.82 CYP1A2 (0.58) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL30801673 0.82 KIF11 (0.50) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL2891974 0.82 NPC1 (0.61) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL9413738 0.82 PEPD (0.46) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL2910974 0.82 ALDH1A1 (0.61) PEPDALDH1A1NPC1MAPTGAA
SCHEMBL24557994 0.82 KMT2A (0.56) ALDH1A1NPC1MAPTGAAKIF11
SCHEMBL5062623 0.81 PEPD (0.80) PEPDALDH1A1NPC1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772540-B2 Thermal responsive molecule KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2014-07-08 US claimed
US-20110124916-A1 THERMAL RESPONSIVE MOLECULE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2011-05-26 US claimed
US-4057588-A Process for the preparation of phloroglucinol AKZONA INCORPORATED (US) 1977-11-08 US claimed
CN-115960352-A Photosensitive polyimide precursor resin, preparation method thereof and photosensitive resin composition 深圳市道尔顿电子材料有限公司 2023-04-14 CN disclosed
US-8772540-B2 Thermal responsive molecule KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2014-07-08 US disclosed
US-8772540-B2 Thermal responsive molecule KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2014-07-08 US disclosed
US-20110124916-A1 THERMAL RESPONSIVE MOLECULE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2011-05-26 US disclosed
US-20110124916-A1 THERMAL RESPONSIVE MOLECULE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2011-05-26 US disclosed
US-4296260-A Process for the preparation of phloroglucinol AKZONA INCORPORATED (US) 1981-10-20 US disclosed
US-4123461-A Benzene-tricarboxylic acid-(1,3,5)-tri-N-chloramide and process for the preparation thereof AKZONA INCORPORATED (US) 1978-10-31 US disclosed
US-4123461-A Benzene-tricarboxylic acid-(1,3,5)-tri-N-chloramide and process for the preparation thereof AKZONA INCORPORATED (US) 1978-10-31 US disclosed
US-4057588-A Process for the preparation of phloroglucinol AKZONA INCORPORATED (US) 1977-11-08 US disclosed
US-4057588-A Process for the preparation of phloroglucinol AKZONA INCORPORATED (US) 1977-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124916-A1 THERMAL RESPONSIVE MOLECULE HEATR1, HEATR6, HSPH1 PEPD 4327/4885ALDH1A1 1972/4885NPC1 4711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.