SCHEMBL561863

SCHEMBL561863

CCC(C)(C)c1ccc(-c2ccc(OP(O)O)c(C(C)(C)CC)c2-c2ccc(C(C)(C)CC)cc2C(C)(C)CC)c(C(C)(C)CC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.42
SMN1; SMN2 Q16637 5/20 0.42
NPSR1 Q6W5P4 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 4/20 0.37
HTT P42858 3/20 0.37
UBE2N P61088 2/20 0.37
GLA P06280 1/20 0.37
MITF O75030 1/20 0.37
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
CASP3 P42574 1/20 0.35
ATM Q13315 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
RAD52 P43351 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958957 0.86 MAPK1 (0.46) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL29489559 0.85 MAPK1 (0.43) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL561156 0.85 MAPK1 (0.43) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL1159942 0.85 MAPK1 (0.37) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL4091307 0.81 MAPK1 (0.55) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL31059273 0.81 MAPK1 (0.55) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL1241928 0.79
SCHEMBL1160379 0.79 NPC1 (0.33) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL27871290 0.79 MEN1 (0.36) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL1159941 0.78 MAPK1 (0.38) MAPK1SMN1; SMN2NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459575-B2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2018-07-25 EP claimed
EP-2459575-B1 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2014-12-17 EP claimed
EP-2459575-A2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS Chemtura Corporation (US) 2012-06-06 EP claimed
US-8048946-B2 Hydrolytically stable phosphite compositions CHEMTURA CORPORATION (US) 2011-11-01 US claimed
WO-2011014529-A2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO claimed
US-20110028619-A1 Hydrolytically stable phosphite compositions SI GROUP, INC. 2011-02-03 US claimed
EP-2459575-B2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2018-07-25 EP disclosed
EP-2491078-B1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING ADDIVANT SWITZERLAND GMBH (CH) 2016-09-28 EP disclosed
US-20150021523-A1 Processes For Forming Alkylated Aryl Phosphite Compositions From Complex Hydrocarbon Streams ADDIVANT USA LLC (US) 2015-01-22 US disclosed
EP-2459575-B1 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2014-12-17 EP disclosed
US-8735628-B2 Processes for forming alkylated aryl phosphite compositions from complex hydrocarbon streams ADDIVANT USA LLC (US) 2014-05-27 US disclosed
US-8258214-B2 Polymers with low gel content and enhanced gas-fading CHEMTURA CORPORATION (US) 2012-09-04 US disclosed
EP-2491078-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING Chemtura Corporation (US) 2012-08-29 EP disclosed
WO-2011014529-A2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
WO-2011014351-A1 PROCESS FOR FORMING ALKYLATED ARYL PHOSPHITE COMPOSITIONS FROM COMPLEX HYDROCARBON STREAMS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
WO-2011014209-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
US-20110024677-A1 Processes for forming alkylated aryl phosphite compositions from complex hydrocarbon streams ADDIVANT USA, LLC 2011-02-03 US disclosed
US-20100197837-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2010-08-05 US disclosed
US-20100069542-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS AND ALKYLATE COMPOSITIONS FOR MANUFACTURING SAME CHEMTURA CORPORATION (US) 2010-03-18 US disclosed
US-20090326112-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2009-12-31 US disclosed