Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | UBE2N | P61088 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489559 | 0.85 | MAPK1 (0.43) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL561156 | 0.85 | MAPK1 (0.43) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL1159813 | 0.81 | — | — | |
| SCHEMBL27958957 | 0.79 | MAPK1 (0.46) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL561863 | 0.78 | MAPK1 (0.42) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL31059273 | 0.77 | MAPK1 (0.55) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL4091307 | 0.77 | MAPK1 (0.55) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL562596 | 0.75 | MAPK1 (0.42) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL1159942 | 0.73 | MAPK1 (0.37) | MAPK1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL1160369 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183311-B2 | Liquid phosphite composition derived from cresols | CHEMTURA CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |
| WO-2011014211-A1 | LIQUID PHOSPHITE COMPOSITION DERIVED FROM META-CRESOLS | CHEMTURA CORPORATION (US) | 2011-02-03 | — | — | WO | disclosed |
| US-20100076125-A1 | LIQUID PHOSPHITE COMPOSITION DERIVED FROM CRESOLS | CHEMTURA CORPORATION (US) | 2010-03-25 | — | — | US | disclosed |