Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376898 | 0.92 | ALDH1A1 (0.46) | TSHRALDH1A1HSD17B10FOLH1 | |
| SCHEMBL10948022 | 0.87 | FOLH1 (0.52) | TSHRALDH1A1HSD17B10FOLH1 | |
| SCHEMBL7710531 | 0.84 | FOLH1 (0.55) | TSHRALDH1A1HSD17B10FOLH1 | |
| SCHEMBL3226093 | 0.84 | ALDH1A1 (0.43) | TSHRALDH1A1HSD17B10FOLH1 | |
| SCHEMBL10630073 | 0.84 | TSHR (0.48) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL8926860 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8376900 | 0.81 | ALDH1A1 (0.68) | TSHRALDH1A1FOLH1 | |
| SCHEMBL7946541 | 0.81 | ALDH1A1 (0.54) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL407915 | 0.81 | — | — | |
| SCHEMBL27791611 | 0.78 | TSHR (0.53) | TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3047274-A2 | PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS | Ohmx Corporation (US) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042493-A2 | PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS | OHMX CORPORATION (US) | 2015-03-26 | — | — | WO | disclosed |
| US-20140322740-A1 | PSA PEPTIDASE ACTIVITY (PPA) AS A PROSTATE CANCER BIOMARKER | NORTHWESTERN UNIVERSITY, AN ILLINOIS NOT FOR PROFIT CORPORATION (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140134658-A1 | PSA ENZYMATIC ACTIVITY: A NEW BIOMARKER FOR ASSESSING PROSTATE CANCER AGGRESSIVENESS | NOTRHWESTERN UNIVERSITY, AN ILLINOIS NOT FOR PROFIT CORPORATION (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2571997-A2 | ENZYMATIC ACTIVITY OF PSA AS DIAGNOSTIC MARKER FOR PROSTATE CANCER | Ohmx Corporation (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20120034638-A1 | Electrochemical assay for the detection of enzymatically active PSA | NORTHWESTERN UNIVERSITY, AN ILLINOIS NOT FOR PROFIT CORPORATION | 2012-02-09 | — | — | US | disclosed |
| WO-2011146143-A2 | DETECTION OF CANCER BY ASSAYING PSA ENZYMATIC ACTIVITY | OHMX CORPORATION (US) | 2011-11-24 | — | — | WO | disclosed |